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Small, compact and cost effective. The GR1 strikes again!

Replacing an expensive Germanium-based Detector with a Kromek GR1 room temperature CZT-based Gamma Spectrometer

Summary

This customer assessed the capability of a HPGe detector alongside Kromek’s smaller, cheaper and easier to use CZT-based GR1 detector in taking the radionuclide purity measurements of PET radiopharmaceuticals.  The results generated by the GR1 were comparable to those of the HPGe, leading the customer to conclude that the GR1 is a more than appropriate tool for quality control applications in Radiopharmacy.

This work was aimed at characterizing and validating a very compact, USB-powered, CZT (CdZnTe) detector for Gamma Ray Spectrometry applications in Radiopharmacy. A Kromek GR1 model was utilized. The detector was calibrated in energy and efficiency.

Samples of [18F]FDG and [68Ga]-DOTANOC were measured to assess the detector’s suitability in radionuclidic purity measurements. The energy resolution and the efficiency obtained are fully adequate for quality control of positron emission tomography radiopharmaceuticals. Results of [18F]FDG and [68Ga]-DOTANOC samples proved to be comparable to those obtained using high-purity Germanium detectors.

The performance of the detector and its very compact size make this type of device an extremely attractive tool for QC applications in radiopharmacy.

The performance of the detector, the very compact size, ease of use, essentially zero maintenance and low power requirements makes the GR1 an extremely attractive tool for QC applications in Radiopharmacy.

The GR1 a viable replacement for expensive Germanium-based Detector

Read the full study and results

You can read the full academic paper here:

Sara Vichi, Angelo Infantino, Gianfranco Cicoria, Davide Pancaldi, Domiziano Mostacci, Filippo Lodi & Mario Marengo (2016) An innovative Gamma Ray Spectrometry system using a compact and portable CZT detector for radionuclidic purity tests of PET radiopharmaceuticals, Radiation Effects and Defects in Solids, 171:9-10, 726-735, DOI: 10.1080/10420150.2016.1253090

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